When the RR was assumed to be independent of age, the estimated BRCA1 breast and ovarian cancer RRs (95% CI) were 15.6 (12.6–19.4) and 39.8 (29.6–53.3), respectively, and the estimated BRCA2 breast and ovarian cancer RRs (95% CI) were 10.3 (8.3–12.7) and 6.8 (3.9–11.9), respectively (Table 1). The gene discussed is BRCA2; the disease is ovarian carcinoma.