Flow cytometry cycle test results showed that the DLBCL cancer cells transfected with GPX4 gene overexpression decreased in G1 phase, rose in S phase, and decreased in G2 phase, indicating that GPX4 gene overexpression led to DLBCL cancer cells' accelerated synthesis in G1 phase but was blocked in S phase, thus affecting DLBCL cancer cells' proliferation (appendix Fig. 3A). Here, GPX4 is linked to diffuse large B-cell lymphoma.