We took the module with the highest total score (Score>14), and a total of 16 key MCODE genes were obtained and spearman correlation analysis was used to analyze the correlation between GPX4 and the 16 key MCODE genes of DLBCL (Fig. 4B), the results showed that all these genes had a negative correlation with GPX4, indicating that the upregulation of this module's key genes promoted the development and occurrence of DLBCL, and there was a significant negative correlation between CDCA7 and GPX4. This evidence concerns the gene CDCA7 and diffuse large B-cell lymphoma.