NFKB1 and kidney disorder: Regarding the effects of each of the above-mentioned main components of FZHY on kidney diseases, we found the following: baicalin can protect the kidneys from injury by suppressing NF-κB-mediated inflammation [72,73], while hydroxysafflor yellow A exerts anti-fibrosis effects by inhibiting TGF-β1-mediated epithelial-to-mesenchymal transition (EMT) in the kidneys [74].