According to our findings, CHST12 expression is positively correlated with the infiltration of immune cells (CD4+ T cells, macrophages, neutrophils, and dendritic cells), which contributes to immunosurveillance, the elimination of tumor cells, and the slowing of immune evasion in the PAAD microenvironment (56, 57). The gene discussed is CHST12; the disease is neoplasm.