ZSCAN12 and endometrial cancer: High analytical specificity with a blank limit of 2 positive droplets and a minimum detection limit of 50 pg of methyl DNA per ml of plasma. hence, high sensitivity. The technique has a high specificity for the identification of EC (endometrial cancer) mainly by hypermethylation of ZSCAN12 (containing zinc finger and SCAN structural domain 12) and oxytocin (oxytocin).