CD4 and myasthenia gravis: Additionally, animal studies have demonstrated that a probiotics mixture (IRT5)—comprising Streptococcus thermophilus, Lactobacillus reuter, Bifidobacterium bifidium, Lactobacillus acidophilus, and Lactobacillus casei—can mitigate pro-inflammatory responses and lower AChR antibody levels in MG rat models by increasing Foxp3+CD4+Treg cells (51).