GC-derived EVs could deliver SNHG12 to human peritoneal mesothelial cells, inducing MMT and further promoting peritoneal metastasis of GC, and further studies showed that SNHG12 promoted peritoneal metastasis through the miR-129-5p/E2F7/MAPK/ERK axis (Zhang et al., 2022a). This evidence concerns the gene SNHG12 and gastric cancer.