NR1H4 and disorder of glycogen metabolism: Recent studies have found that Order Lactobacillales may promote farnesoid X receptor (FXR) activation by lowering intestinal tauro-α-muricholic acid (T-α-MCA) and tauro-β-MCA (T-β-MCA) concentrations, reducing bile acids (BAs) and cholesterol synthesis in the liver and thereby reducing the incidence of GSD (Ye et al., 2022).