INS and diabetes mellitus: In respect to safety, patients in our study were most concerned with (1) having a clear understanding of alerts and warnings, (2) being able to recognize and rapidly respond to a potentially life-threatening situation (eg, device overrides, function lockdowns, and system-down alerts), (3) knowing immediately if there were device connectivity issues that impede overall diabetes management (eg, the continuous glucose monitor not connected to the insulin pump), and (4) having safeguards to reduce the risk of user error (eg, data field restrictions and order entry confirmation requirements).