Although there is currently a lack of epidemiological data on TTR mutations in Turkey, a recent diagnostic study using multicenter next-generation sequencing (NGS) technology was conducted at 23 centers across Turkey suggested that TTR mutations were rare in Turkey, with only one TTR mutation identified among 392 patients with hypertrophic cardiomyopathy (HCM) (12). This evidence concerns the gene TTR and hypertrophic cardiomyopathy.