Autoantibodies against prohibitin 1 were first described in people with dacryosialoadenopathy (Mikulicz’s disease), type 1 AIP, and retroperitoneal fibrosis, with predominant manifestations of IgG4-RD in bicarbonate-secreting glands (13). This evidence concerns the gene PHB1 and immunoglobulin G4-related sclerosing disease.