Similarly, the S°S Signature CETP+CMTM5+MIA-MPP3-PLA2G7 was evaluated using five Sepsis datasets: GSE154918, GSE131761, GSE9960, GSE28750 and GSE65682 alongside other biomarker combinations performing well for ABDM sepsis (CMTM5+ITGB3-ARHGEF10L-GPR124-PLA2G7); PLMN sepsis (CETP+MIA+PLXNB3-MPP3) and two larger panels combining 8 of the best performing biomarkers (CMTM5+ITGB3-PLA2G7-ARHGEF10L-GPR124+CETP+MIA-MPP3) and (CMTM5+ITGB3-PLA2G7-ARHGEF10L+CETP+MIA+PLXNB3-MPP3), given in Supplementary Information 5-Supplementary Table 5.4. The gene discussed is CMTM5; the disease is Sepsis.