ANN confirmed importance of the SIRS/sepsis discriminatory biomarkers, including ARHGEF10L, PLA2G7, PLXNB3, MPP3 and CETP for discriminating SIRS from ABDM (Supplementary Information 2-Supplementary Table 2.11) and PLMN sepsis (Supplementary Information 2-Supplementary Table 2.12). The gene discussed is PLXNB3; the disease is systemic inflammatory response syndrome.