CD274 and neoplasm: Innate immunity-related transcripts (ifne, ifnz, Cxcl10), the corresponding transcript for the DNA sensor cGAS (Cgas), major histocompatibility complex (MHC)-related transcripts (H2-Eb1, H2-DMb1), the clinically relevant transcript for the target PD-L1 (Cd274), and a fat and glucose metabolism associated transcript (Fgfbp3), as well as tumor suppressors (Btg2, Pmm1), were significantly overexpressed in conjugate-I-treated cells, suggesting that conjugate I is able to promote an immune reaction in cancer cells and affect metabolism-related pathways, which may facilitate anticancer immunity.