STING1 and neoplasm: CDDP and MSA-2 might be natural partners in a single-molecule multitarget drug design, as CDDP induces DNA fragment release during tumor cell killing [16], facilitating the remote activation of the cGAS-STING pathway in tumor-infiltrating immune cells, while MSA-2 could further enhance downstream intracellular STING signaling (Fig. 1D).