As for the discrimination between FTD and SMC_CTR, the single biomarker diagnostic models shows that though Tau and pTau levels are able to discriminate FTD from controls with sufficient accuracy (AUC Tau = 0.804; AUC pTau = 0.697), Aβ42 (AUC 0.581) does not discriminate at all (Figure 2B), as expected. The gene discussed is MAPT; the disease is frontotemporal dementia.