In the comparison AD vs. FTD, the inclusion of NGF or NGF + proNGF as predictors does not change the diagnostic performance, as evident from the ROC curves (see Supplementary Figure 2 and Figure 5B) and AUC values (AUC = 0.863 for diagnostic model ∼ Aβ42 + Tau + pTau; AUC = 0.883 for diagnostic model ∼ Aβ42 + Tau + pTau + NGF; AUC = 0.800 for diagnostic model ∼ Aβ42 + Tau + pTau + proNGF + NGF). The gene discussed is NGF; the disease is frontotemporal dementia.