Declined transmission of ALKBH7 further indicated that ALKBH7 content of TAAs to transfer TMZ resistance to glioblastoma cells decreased obviously (Figure 5C), which implied that ALKBH7 can regulate APNG expression, knocking‐down of ALKBH7 expression remarkably reduced APNG level (Figure 5D). This evidence concerns the gene ALKBH7 and glioblastoma.