IFNG and neoplasm: Given the dramatically reduced α-Galactosylceramide (αGC)-induced IFN-γ production in splenic iNKT cells and intratumoral iNKT cells from Cd11ccreCd1dfl/fl mice but enhanced IFN-γ production in those cells from Lyz2creCd1dfl/fl mice (Fig. 2b, c, Supplementary Fig. 1a and Supplementary Fig. 2a, b), DCs were predominant antigen presenting cells activating and inducing Th1 anti-tumor response of iNKT cells in tumors as well as in spleens in vivo.