Recently we used a unique tissue collection of brain tissues from idiopathic PD (IPD) patients and PD patients carrying a GBA1 mutation (PD-GBA) to perform a non-targeted lipidomics analysis of four different brain regions13, namely the striatum (STR), which is part of the nigrostriatal dopaminergic pathway, and also the occipital cortex (OCC), middle temporal gyrus (MTG) and cingulate gyrus (CG). This evidence concerns the gene GBA1 and Parkinson disease.