ILF2 and Miyoshi myopathy: We also observed that ILF2 depletion sensitized MM cells to bortezomib (Fig. 1D; Supplementary Fig. 1F), which is consistent with previous findings showing that bortezomib impairs homologous recombination13, thus enhancing the effect of ILF2 depletion on the ability of MM cells to repair DNA damage8.