RRS1 and neoplasm: To further investigate the mechanism of SNHG1 action in BC, we utilized the targetScan database (https://www.targetscan.org/vert_72/) to identify miR-641's downstream target gene RRS1. Analysis using the GEPIA database (http://gepia.cancer-pku.cn/), revealed elevated RRS1 mRNA levels in BC tumor tissues compared to normal tissues in the TCGA cohort (Fig. 4A).