NECTIN4 and infection: Pre-existing humoral α-RABV immunity collapsed within 3 weeks of recCDV NΔ425-479 infection and was not restored over a 3-month post-recovery period (Fig. 2g), whereas recCDV Nectin-4-blind caused only a temporary moderate decline in α-RABV nAbs titers that spontaneously resolved within 4 weeks of infection.