To further determine whether the high expression of UPP1 in tumor cells contributes to immunosuppression through specific ligands such as cytokines or chemokines, we conducted an assessment of alterations in cytokine expressions in the LUAD cell line overexpressing UPP1 using the high-throughput 80-cytokine array (Fig. 3a). The gene discussed is UPP1; the disease is neoplasm.