NSG mice were subcutaneously injected with 1.0 × 106 Raji cells mixed with Geltrex and when tumor size reached 50 mm2, mice were treated twice (three days in between) with 1.0 × 107 MOCK control NK cells, CD70-CAR NK cells, or CD70-CAR-IL-15 NK cells or left untreated (Fig. 4A). Here, CD70 is linked to neoplasm.