Cytotoxic capacity of CD70-CAR NK cells was further evaluated against three > 95% CD70+ hematological and solid tumor cell lines, of which a Burkitt’s lymphoma-derived cell line (Raji; ΔMFICD70: 15,429,891.3 ± 383,907.9) displayed highest CD70 surface density, a PDAC-derived cell line (PANC-1; ΔMFICD70: 440,510.0 ± 96,692.9) intermediate CD70 density and a CRC cell line derived from a metastatic lesion (LIM2099; ΔMFICD70: 248,192.0 ± 77,270.6) low CD70 density (Fig. 2E, F, G). The gene discussed is CD70; the disease is Burkitt lymphoma.