Among all participants, significant interactions with alcohol intake as a continuous variable (units per week) were observed for association with serum urate level at rs1229984 in the ADH1B locus (P = 3.0 × 10−44) and rs6460047 in the MLXIPL locus (P = 1.4 × 10−4) (Table 3; and Additional file 1: Table S5), and for association with hyperuricaemia at ADH1B rs1229984 only (P = 7.9 × 10−13) (Table 4; and Additional file 1: Table S6). Here, ADH1B is linked to hyperuricemia.