Recent study results by Bertelsen et al. provided evidence that IL-17F plays a key role in the IL-23/IL-17 axis26 have shown that IL-17F stimulation induces the expression of IκBκ, whose critical role in psoriasis pathogenesis has been previously demonstrated27 in human keratinocytes by changing both mRNA and protein levels, and plays a role in the regulation of many genes such as psoriasis associated.26 This evidence concerns the gene IL37 and psoriasis.