Both the receptors VEGFR and FGFR and their ligands VEGF and PDGF are highly expressed in head and neck tumors and the high expression of PDGF can promote the expression of VEGF.14, 15 The high expression of VEGF plays an important role in the formation of tumor blood vessels and the growth of tumor cells.10 The gene discussed is VEGFA; the disease is head and neck neoplasm.