Throughout gestation, compared to the reference women, women with IH at 12 weeks gestation had persistently and significantly higher mean (log)CRP, F (1): 14.8, P < 0.001 (Fig. 4A), and mean logIL-6, F = 12.5, P < 0.001 (Fig. 4B); they showed persistently and significantly lower mean (log)ferritin, F (1): 4.8, P = 0.034 (Fig. 4C), and mean (log)hCG, F (1) = 12.8, P < 0.001 (Fig. 4D) throughout gestation. This evidence concerns the gene CRP and isolated hemihyperplasia.