However, we did not detect other genetic abnormalities common in PCa and presented in the literature, such as mutations of genes involved in the repair of DNA damage (BRCA1/2, ATM, BAP1, RAD50, FANCE, PALB2), chromatin remodeling (ARID1A, PBRM1, ARID2, KMT2D, KMT2C, SMARCA4, SETD2) and cell cycle control pathways (CDKN2A, CCND1, CCNE1), as well as in Ink4a, LKB1, MLH1, PRSS1, BRAF, MAPK, PI3K, Akt, VEGF and IGF1R genes. The gene discussed is PRSS1; the disease is posterior cortical atrophy.