Inoculation of human-induced pluripotent stem cell (hiPSC)-derived neurogenin-2 (Ngn2) neuronal co-cultures, consisting of neurons and astrocytes that both lack MeV receptors CD150 and nectin-4, led to productive infection and replication of both rMeVSSPE-F and rMeVF-N465I (Fig. 5D). This evidence concerns the gene SLAMF1 and infection.