We found that, while most secreted cytokines were at comparable levels between CTL and L2-PD, IL-6 was significantly higher in the culture medium of unstimulated L2-PD astrocytes as compared with CTL and was similar to CTL cytokine-stimulated astrocytes (Figure 2, A and B [P < 0.01 and P < 0.001], and Supplemental Figure 2A), suggesting a specific upregulation of IL-6 in L2-PD astrocytes. The gene discussed is IL6; the disease is Parkinson disease.