<p align=”left”>Rare<em>&nbsp;RBCK1/HOIL-1L</em>&nbsp;variant&nbsp;is a systemic lupus erythematosus susceptibility gene that augments&nbsp;linear ubiquitin assembly complex&nbsp;function via attenuation of HOIL-1L ligase.</p>. Here, RBCK1 is linked to systemic lupus erythematosus.