Further, analysis of cortical T-ALL yielded differentially expressed genes with CD1A, CD1C, CD4, CFTR, FAT3, NKX2-1, TLX1, TLX3, and RAG1 being reported earlier in various reports, while EREG, PAX6, and ZIC2 were identified to be up-regulated in the present study. This evidence concerns the gene NKX2-1 and acute lymphoblastic leukemia.