Among the genetic causes of dystonia, the efficacy of GPi-DBS also varies based on the specific monogenic form, with generalized dystonia (DYT-TOR1A), myoclonus dystonia (DYT-SCGE), and X-linked dystonia Parkinsonism (DYT/PARK-TAF1) showing good outcomes and other isolated and combined dystonias (DYT-THAP, DYT-GNAL, DYT-KMT2B, DYT-ATP1A3, and DYT-ANO3) showing suboptimal responses (18). The gene discussed is ANO3; the disease is Dystonia.