Four unique GEARs (dfrA17, TEM-1, aph(3′′)-Ib, and aph(6)-Id in pEcoUTI1d) for UTI-1774 U and 2 GEARs (dfrA1, sat2, and aadA1 in pEcoUTI2f) in the UTI-2_245U strain were identified (Figure 6A). Here, APEH is linked to bacterial urinary tract infection.