PDPN and cancer: FB2 showed upregulation of NF-kappa B signaling pathway genes, NFKBIA, NFKB1, and NFKBIZ (logFC >0.4), VEGFA-VEGFR2 signaling pathway gene, VEGFA (logFC = 0.3), chemokine receptor genes, IL6 (logFC = 1.7) and CCL2 (logFC = 1.7), transmembrane glycoprotein genes, PDPN (Neri et al., 2015) (logFC = 0.1), and genes associated with cancer metastasis, IER3 (Ye et al., 2018) (logFC = 0.6), SGK1 (Sang et al., 2021) (logFC = 1), and SERPINE2 (Yang et al., 2018) (logFC = 0.5).