NA inhibitors are the most widely used anti-influenza agents that inhibit the enzymatic activity of neuraminidases of Influenza A and Influenza B viruses (IAV) and (IBV) [52], preventing the cleavage in sialic acid residues on viral and host cell surfaces, blocking the virions binding on the host cell surface, resulting in virion replication cycle arrest [53], [54]. This evidence concerns the gene XK and influenza.