The most cited article (“IL-23 induces spondyloarthropathy by acting on ROR-γt + CD3 + CD4-CD8-entheseal resident T cells”), which was published in Nature Medicine in 2012, has an IF = 82.9, suggesting that IL-23 and the immune system have an important role in diseases caused by BTI abnormalities (31). Here, CD4 is linked to spondyloarthropathy.