DHX9 and Anxiety: Consistent with previous reports,30 nerve injury significantly anxiety-like behaviors as tested by the decreased entries into open arms and the time in open arms (Figures 7F–7H), and overexpression of DHX9 with AAV significantly revered the CCI-induced decrease of entries number into open arms (Figure 7F), and the bias in time in open arms (Figure 7G), compared with the Gfp group.