The upregulated nucleoli genes in ApoE–/– HFD at 6 weeks, 32 weeks, and 78 weeks, ApoE–/– Ang II-AAA at 7days, 14 days, and 28 days, human MI, human AAA, and human AOD were shown in the Supplementary Figures S2F–J. This evidence concerns the gene APOE and triple-A syndrome.