Th1 (IRF1); Th2 (IL-4R, CCL18, CCL26); Th17 (IL-17A, IL-23A) and Th22 (IL-22) related genes and many others were upregulated in ADInflammatory markers such as CRP; Ferritin and eosinophils were elevated in African American AD compared to healthy controls and European American AD. The gene discussed is IRF1; the disease is Alzheimer disease.