Moreover, a cross-sectional study involving 673 CAD patients found that low Montreal Cognitive Assessment (MoCA) scores in CAD patients (age 66.3 ± 6.5 years, 24% of females, systolic blood pressure 140.5 ± 27 mm Hg) were associated with a lower level of brain-derived neurotrophic factor (BDNF) released by platelets in the serum (20). Here, BDNF is linked to coronary artery disorder.