Lactobacillales are known for their beneficial effects in insects, such as their ability to mediate insecticide resistance (Xia et al. 2013), modulate the microflora composition to protect the host against infections (Ouwehand et al. 2002), promote intestinal peptidase expression, increase intestinal proteolytic activity (Erkosar et al. 2015) and enhance the systemic production of host ecdysone and insulin-like peptides (Storelli et al. 2011). The gene discussed is LAP3; the disease is infection.