MAPT and Alzheimer disease: Intracerebral inoculation of Tau PFF purified from AD brains (AD‐Tau) resulted in robust Tau inclusions in anatomically connected brain regions in non‐transgenic mice.[2d,f] We extracted AD‐Tau, seeded recombinant Tau (5/95%) for fibrillization, and sonicated to obtain Tau PFF as published.[2d] We characterized the Tau‐PFF with transmission electron microscopy (TEM) (Figure S1a,b, Supporting Information) and thioflavin T (ThT) assay (Figure S1c,d, Supporting Information).