The BP-enriched pathways include the dilated (DCM), hypertrophic (HCM) and arrhythmogenic right ventricular cardiomyopathy (ARVC) pathways, thirty (30) signaling pathways, among which the adrenergic signaling in cardiomyocytes and the PI3K-Akt, the Rap1, the cGMP-PKG, the cAMP, the HIF-1 (hypoxia-inducible factor 1) and the calcium signaling pathways, four (4) focal adhesion/axon guidance-related pathways, the vascular smooth muscle contraction and the regulation of actin cytoskeleton pathway. Here, AKT1 is linked to Arrhythmogenic right ventricular dysplasia.