Analysis of the data showed that the expression levels of IGFBP3 and PD-L1 have a low association in LGG (R = 0.14, P = 0.0014) while they have high association in GBM patients (R = 0.32, P = 1.2e−08) (Fig. 1C). This evidence concerns the gene IGFBP3 and glioblastoma.