The OS in our data set is slightly longer than the reported survival of IDH1/2 wt astrocytomas (23.8 months) in a cohort of 67 patients and considerably shorter than the OS of IDH1/2 wt astrocytomas WHO II (59 months) [1, 17, 26, 27]. The gene discussed is IDH1; the disease is astrocytoma (excluding glioblastoma).