Moreover, although NK and CD8+ T cells recruited to liver tumours of wild-type mice produce IFNγ and TNF (Fig. 4k), the production of IFNγ and TNF was reduced in the remaining NK and CD8+ T cells present in the liver of tumour-bearing Clec4fcreId3f/f mice (Fig. 4k). Here, CD8A is linked to neoplasm.