Depletion of CD8 and NK cells with antibodies increased tumour growth in wild-type mice, but not to the level of Clec4fcreId3f/f mice, and did not further increase tumour growth in Clec4fcreId3f/f mice (Fig. 4l), suggesting that both phagocytosis and the recruitment and/or activation of effector lymphoid cells contribute to the anti-tumour activity of KCs. The gene discussed is TBCE; the disease is neoplasm.