The upregulation of BAX and CASP9 genes in AGS cell line was also dramatically higher than the expression of the same genes in HT-29 cell line after 72 h of treatment, demonstrating that the occurrence of apoptosis was higher in AGS treated cells compared to HT-29 treated cancer cell line (P < 0.05 for BAX and P < 0.0001 for CASP9). The gene discussed is CASP9; the disease is cancer.