For example, one study identified a risk score derived from nine cuproptosis-related lncRNAs (LRRC8C-DT, TDRKH-AS1, SAMMSON, SIAH2-AS1, WDFY3-AS2, LINC00393, ARHGAP28-AS1, PCAT18, LINC01711), establishing it as an independent prognostic factor for BC and a potential indicator for immunotherapy response23. This evidence concerns the gene SIAH2 and breast cancer.