More recently, a retrospective analysis of 6,130 iCCA patients from the FoundationCORE database reported that FGFR2 p.C382R, p. F276C and p.Y375C point mutations are common molecular events in iCCA, occurring in 22.7%, 22% and 19.9% of cases, respectively15. The gene discussed is FGFR2; the disease is infantile convulsions and choreoathetosis.