Cell Titer Glo assays identified inhibitory concentrations of CB-5083 in both FU-UR-1 and ASPS-1 cells as well as control cancer cell lines HCT116 (colorectal carcinoma), ASKA (synovial sarcoma), and two cell lines that natively express other TFE3 fusions, UOK146 that expresses PRCC-TFE3 and UOK109 that expresses NONO-TFE3 (Supplementary Fig. 6f). This evidence concerns the gene TFE3 and cancer.